ACUTE LETHAL AND SUBLETHAL EFFECTS OF DILTIAZEM AND DOXEPIN FOR FOUR AQUATIC ENVIRONMENTAL BIOINDICATORS COVERING THE TROPHIC CHAIN

Acute lethal and sublethal effects of diltiazem and doxepin for four aquatic environmental bioindicators covering the trophic chain

Pharmaceuticals are becoming an environmental and health problem of concern.We present here the results obtained in the ecotoxicological evaluation of two drugs (diltiazem and doxepin) recurrently present in the environment.To carry out this study, four aquatic bioindicators (Vibrio fischeri, Daphnia magna, Selenastrum capricornutum, and Danio reri

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The Impact of Prescribing Monitoring Policy on Drug Use and Expenditures in China: A Multi-center Interrupted Time Series Study

Background A prescribing monitoring policy (PMP) was implemented in November 2015 in Anhui province, China, the first province to pilot this policy to manage the use and costs of select drugs based on their large prescription volumes and/or costs in hospitals.This study evaluated the impact of PMP on the use and expenditures of different drugs in t

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